Products related to Specificity:
-
New Experimental Probes for Enzyme Specificity and Mechanism : Volume 685
New Experimental Probes for Enzyme Specificity and Mechanism, Volume 685, the latest release in the Methods of Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics including Subverting Hedgehog Protein Autoprocessing by Chemical Induction of Paracatalysis, New Mechanistic Probes to Identify Novel Substrates for N-Myristoyltransferases, Phosphonate and a Fluorophosphonate Analogues of D Glucose 6 Phosphate as Active-Site Probes of 1L-Myo-Inositol 1 phosphate Synthase, Kinetic Mechanism of Nicotine-Degrading Enzyme Probed by Stopped-Flow Kinetic Analyses, Kinetics and Mechanism for Enzyme-Catalyzed Reactions of Substrate Pieces, and more. Additional chapters cover Kinetics and Mechanism for Reactions of Enzyme Pieces, Evaluation of allostery for the bienzyme assembly of a 3-deoxy-D-arabino heptulosonate-7-phosphate synthase and chorismate mutase, Recognition and Catalysis of Reactions of Chiral Substrates by Mandelate Racemase, Innovative and emerging modalities of EGFR kinase inhibitors, Characterization of the Aminoacrylate Intermediate of Tyrosine Phenol-Lyases, and much more.
Price: 138.00 £ | Shipping*: 0.00 £ -
Ligand-Binding Basics : Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity
A concise and accessible textbook covering ligand-binding theory in chemistry, biology, and drug development In Ligand-binding Basics: Evaluating Intermolecular Affinity, Specificity, Stoichiometry, and Cooperativity, accomplished chemist Jannette Carey introduces ligand binding in a thorough and practical way for those new to the topic, as well as anyone seeking a connection between theory and experiment.Using a minimum of mathematical formalism, this book offers analytical rigor while remaining accessible to non-specialist practitioners.It provides readers with the skills they need to analyze their own binding data or published results, helping them develop an intuitive grasp of ligand-binding phenomena integrated with structural and thermodynamic understanding.Topics covered include: Application of the principles of equilibrium, mass action, and mass balance to derive the basic equations that describe all binding processesRecommended approaches for plotting and graphical analysis of binding dataStrategies for designing, analyzing, interpreting, and troubleshooting experiments from the perspective of ligand-binding theoryReview of selected examples that illustrate integration of structural and thermodynamic analysis Perfect for students and educators in chemistry, biochemistry, molecular biology, and pharmaceutical science, Ligand-binding Basics will also appeal to practitioners who aim to study ligand binding in any molecular system.
Price: 80.00 £ | Shipping*: 0.00 £ -
Streaming Music : Practices, Media, Cultures
Streaming Music examines how the Internet has become integrated in contemporary music use, by focusing on streaming as a practice and a technology for music consumption.The backdrop to this enquiry is the digitization of society and culture, where the music industry has undergone profound disruptions, and where music streaming has altered listening modes and meanings of music in everyday life.The objective of Streaming Music is to shed light on what these transformations mean for listeners, by looking at their adaptation in specific cultural contexts, but also by considering how online music platforms and streaming services guide music listeners in specific ways.Drawing on case studies from Moscow and Stockholm, and providing analysis of Spotify, VK and YouTube as popular but distinct sites for music, Streaming Music discusses, through a qualitative, cross-cultural, study, questions around music and value, music sharing, modes of engaging with music, and the way that contemporary music listening is increasingly part of mobile, automated and computational processes.Offering a nuanced perspective on these issues, it adds to research about music and digital media, shedding new light on music cultures as they appear today.As such, this volume will appeal to scholars of media, sociology and music with interests in digital technologies.
Price: 43.99 £ | Shipping*: 0.00 £ -
Autobiographical Memory Specificity and Psychopathology : A Special Issue of Cognition and Emotion
It has been repeatedly demonstrated that depression and reported history of trauma are associated with a difficulty in retrieving specific autobiographical memories, a phenomenon called overgeneral memory (Williams & Broadbent, 1986).Over the past twenty years there has been a stimulating progression in knowledge in this field, and it is clear that the topic has a considerable level of importance, both from a theoretical and clinical perspective.This Special Issue is intended to further advance this field which lies at the heart of the cognition-emotion interface.Papers published in this Issue address key issues relating to the underlying mechanisms and aetiology of overgeneral autobiographical memory, providing a state-of-the-art and pushing the field forward.
Price: 32.99 £ | Shipping*: 0.00 £
-
What are substrate specificity and activity specificity using the example of restriction enzymes?
Substrate specificity refers to the ability of an enzyme to recognize and bind to a specific substrate molecule. In the case of restriction enzymes, they have substrate specificity for particular DNA sequences, known as recognition sites. For example, the restriction enzyme EcoRI recognizes and binds to the DNA sequence GAATTC. Activity specificity, on the other hand, refers to the specific chemical reaction that an enzyme catalyzes. In the case of restriction enzymes, their activity specificity is to cleave the DNA at specific recognition sites. For example, EcoRI cleaves the DNA at the GAATTC sequence. In summary, substrate specificity refers to the ability of an enzyme to recognize and bind to a specific substrate molecule, while activity specificity refers to the specific chemical reaction that the enzyme catalyzes. In the case of restriction enzymes, they have substrate specificity for specific DNA sequences and activity specificity to cleave the DNA at those sequences.
-
What is the actual difference between catalytic specificity and substrate specificity in enzymes?
Catalytic specificity refers to the ability of an enzyme to catalyze a specific chemical reaction, while substrate specificity refers to the ability of an enzyme to bind to a specific substrate. In other words, catalytic specificity is about the type of reaction that an enzyme can catalyze, while substrate specificity is about the specific molecule that an enzyme can bind to and act upon. Enzymes can have different levels of specificity for both their catalytic activity and their substrate binding, which allows them to carry out specific functions in the cell.
-
What is the substrate specificity of enzymes?
The substrate specificity of enzymes refers to the ability of an enzyme to recognize and bind to a specific substrate molecule. Enzymes are highly specific in their interactions with substrates, as they have active sites that are uniquely shaped to accommodate specific substrates. This specificity ensures that enzymes only catalyze specific reactions and do not interact with other molecules in the cell. Substrate specificity is crucial for the efficiency and regulation of biochemical reactions in living organisms.
-
What is the group specificity of enzymes?
Group specificity of enzymes refers to the ability of an enzyme to act on a specific functional group within a substrate molecule. This means that the enzyme can only catalyze a reaction involving a particular functional group, such as an alcohol or an amine. Enzymes with group specificity are highly selective and only interact with substrates that contain the specific functional group that they are designed to act upon. This specificity is important for the regulation and control of biochemical pathways in living organisms.
Similar search terms for Specificity:
-
Content Production for Digital Media : An Introduction
This book provides an introduction to digital media content production in the twenty-first century.It explores the kinds of content production that are undertaken in professions that include journalism, public relations and marketing.The book provides an insight into content moderation and addresses the legal and ethical issues that content producers face, as well as how these issues can be effectively managed.Chapters also contain interviews with media professionals, and quizzes that allow readers to consolidate the knowledge they have gathered through their reading of that chapter.
Price: 69.99 £ | Shipping*: 0.00 £ -
Digital Satire in Latin America : Online Video Humor as Hybrid Alternative Media
How creators of online video critique politics and society and amplify public discourse in Latin American countries This book analyzes how digital-native audiovisual satire has become increasingly influential in national public debates within Latin America.Paul Alonso illuminates the role of online video in filling gaps in sociopolitical critique left by television, traditional journalism, and commercial entertainment while exposing some of the prevalent tensions of the region.Alonso draws on interviews and analyzes media content to consider some of the most representative and influential satirical shows born on the internet and produced in Argentina, Colombia, Ecuador, Peru, Mexico, and Latinx communities in the United States.He discusses YouTubers Chumel Torres, Malena Pichot, Guille Aquino, Joanna Hausmann, and El Cacash; the Enchufe.tv collective; and the video columnists Maria Paulina Baena from La Pulla and Mariángela Urbina from Las Igualadas.These creators use professional and non-mainstream practices and resources to dismantle fake news, highlight social tensions, and offer in-depth content that goes beyond confrontational attacks.In contexts of highly ideological polarization, Alonso argues, digital satire is a unique type of hybrid alternative media that can articulate nonpartisan interpretations of reality while also questioning, deconstructing, and subverting the authoritative role of media.Satiric voices can offer an informed, reflexive, argumentative, or historically rooted perspective that amplifies public discourse and shapes changing notions of journalism and political communication in democratic societies. A volume in the series Reframing Media, Technology, and Culture in Latin/o America, edited by Héctor Fernández L’Hoeste and Juan Carlos Rodríguez Publication of this work made possible by a Sustaining the Humanities through the American Rescue Plan grant from the National Endowment for the Humanities.
Price: 91.00 £ | Shipping*: 0.00 £ -
Digital Satire in Latin America : Online Video Humor as Hybrid Alternative Media
How creators of online video critique politics and society and amplify public discourse in Latin American countries This book analyzes how digital-native audiovisual satire has become increasingly influential in national public debates within Latin America.Paul Alonso illuminates the role of online video in filling gaps in sociopolitical critique left by television, traditional journalism, and commercial entertainment while exposing some of the prevalent tensions of the region.Alonso draws on interviews and analyzes media content to consider some of the most representative and influential satirical shows born on the internet and produced in Argentina, Colombia, Ecuador, Peru, Mexico, and Latinx communities in the United States.He discusses YouTubers Chumel Torres, Malena Pichot, Guille Aquino, Joanna Hausmann, and El Cacash; the Enchufe.tv collective; and the video columnists Maria Paulina Baena from La Pulla and Mariángela Urbina from Las Igualadas.These creators use professional and non-mainstream practices and resources to dismantle fake news, highlight social tensions, and offer in-depth content that goes beyond confrontational attacks.In contexts of highly ideological polarization, Alonso argues, digital satire is a unique type of hybrid alternative media that can articulate nonpartisan interpretations of reality while also questioning, deconstructing, and subverting the authoritative role of media.Satiric voices can offer an informed, reflexive, argumentative, or historically rooted perspective that amplifies public discourse and shapes changing notions of journalism and political communication in democratic societies. A volume in the series Reframing Media, Technology, and Culture in Latin/o America, edited by Héctor Fernández L’Hoeste and Juan Carlos Rodríguez Publication of this work made possible by a Sustaining the Humanities through the American Rescue Plan grant from the National Endowment for the Humanities.
Price: 28.95 £ | Shipping*: 0.00 £ -
The Arena Concert : Music, Media and Mass Entertainment
The Arena Concert: Music, Media and Mass Entertainment is the first sustained engagement with what might said to be - in its melding of concert and gathering, in its evolving relationship with digital and social media, in its delivery of event, experience, technology and star - the art form of the 21st century.This volume offers interviews with key designers, discussions of the practicalities of mounting arena concerts, mixing and performing live to a mass audience, recollections of the giants of late twentieth century music in performance, and critiques of latter-day pretenders to the throne.The authors track the evolution of the arena concert, consider design and architecture, celebrity and fashion, and turn to feminism, ethnographic research, and ideas of humour, liveness and authenticity, in order to explore and frame the arena concert.The arena concert becomes the “real time” centre of a global digital network, and the gig-goer pays not only for an immersion in (and, indeed, role in) its spectacular nature, but also for a close encounter with the performers, in this contained and exalted space.The spectacular nature of the arena concert raises challenges that have yet to be fully technologically overcome, and has given rise to a reinvention of what live music actually means. Love it or loathe it, the arena concert is a major presence in the cultural landscape of the 21st century.This volume finds out why.
Price: 140.00 £ | Shipping*: 0.00 £
-
What is the biosubstrate specificity of bonds?
The biosubstrate specificity of bonds refers to the ability of enzymes to selectively bind to specific substrates and catalyze specific chemical reactions. Enzymes have specific active sites that are complementary to the shape and chemical properties of their substrates, allowing them to form temporary bonds and facilitate the conversion of substrates into products. This specificity is crucial for the regulation of biochemical pathways and the overall functioning of biological systems. It ensures that the right reactions occur at the right time and in the right place within the cell.
-
What is the specificity of enzymes on substrates?
Enzymes are highly specific in their interactions with substrates, meaning that each enzyme typically catalyzes a specific chemical reaction with a specific substrate. This specificity is due to the unique three-dimensional shape of the enzyme's active site, which is complementary to the shape and chemical properties of its specific substrate. The enzyme-substrate interaction is often compared to a lock and key, where the enzyme (lock) can only bind to its specific substrate (key) due to their precise matching shapes and chemical properties. This specificity ensures that enzymes can efficiently catalyze specific reactions without interfering with other cellular processes.
-
What does the term cell type specificity mean?
Cell type specificity refers to the unique characteristics and functions of a particular type of cell within an organism. It means that certain cells are specialized to perform specific tasks or functions within the body, and they have distinct molecular and structural features that enable them to carry out these functions. This specificity allows for the coordination and regulation of various physiological processes within the organism, as different cell types can perform their specialized roles in a coordinated manner. Understanding cell type specificity is important for studying the development, function, and dysfunction of different tissues and organs in the body.
-
Could you please provide an urgent response regarding specificity of action?
Specificity of action refers to the ability of a treatment or intervention to target a particular problem or condition without affecting other parts of the body. It is important to consider the specificity of action when choosing a treatment to ensure that it effectively addresses the intended issue without causing unnecessary side effects or harm to other areas. It is also important to consult with a healthcare professional to determine the most appropriate and specific treatment for a particular condition.
* All prices are inclusive of VAT and, if applicable, plus shipping costs. The offer information is based on the details provided by the respective shop and is updated through automated processes. Real-time updates do not occur, so deviations can occur in individual cases.